substances released by muscle tissue in response to exercise be known as myokines. Since IL-6, many other myokines have been identified. They have abbreviations like LIF, IL-4, and BDNF, and each one is thought to summon a different exercise response in the body. Muscle cells now are thought to have the capacity to secrete hundreds of different compounds, each of which has its own peculiar communication function. A similar range of complexity exists for the substances secreted by fat cells.