the real reason that CRISPR exploded onto the biotech scene with such force and vitality was its low cost and ease of use. CRISPR finally made gene editing available to all scientists. Previous tools—primarily ZFNs and TALENs—were difficult to design and prohibitively expensive. For this reason, many labs, including my own, were unwilling to take on the challenges of research using gene editing. With CRISPR, however, scientists can easily design a version to target their gene or genes of interest, prepare the requisite Cas9 protein and guide RNA, and execute the experiments themselves using
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