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If we changed the twenty-letter RNA code to match the sequence of a specific human gene and then transplanted Cas9 and the new guide RNA into human cells, CRISPR would make a surgical cut in the targeted gene, marking that site for repair. By slicing the DNA apart, CRISPR would be acting like a red alert triggering the cell to fix the damage, but in a way that we could control.
A Crack In Creation: A Nobel Prize Winner's Insight into the Future of Genetic Engineering
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