Not only can the master clock desynchronize from the day-night cycle of the sun, but individual organ clocks can desynchronize from one another. For example, the SCN master clock can become desynchronized from the clocks in the intestine, the liver, the pancreas, and other organs that regulate digestion and metabolism. That’s because the latter group of clocks can be set by meal timing, and as far as they’re concerned, the meal signal is stronger than the one coming from the SCN.

