A protein called DNA methyltransferase 1, or DNMT1, is responsible for copying the original DNA methylation pattern to the newly formed strands. DNMT1 recognizes and binds specifically to CpG sites that are asymmetrically methylated. It then adds a methyl group to the naked C base on the new DNA strand, restoring the original cell’s symmetrical methylation pattern. This process is crucial to maintaining the epigenetic landscapes of mature cells and preventing the reversal of cell differentiation. DNA methylation is the best-known example of a mitotically heritable epigenetic modification
