We should make the point that in order for such effects to be of evolutionary significance in the same sense as true mutations, they would have to be passed on not just to the grandchild generation but indefinitely through future generations. In fact, to the extent that they occur at all, they seem to die away over generational time. This is why we expect all adaptive evolution to be caused by Darwinian natural selection on the DNA sequence. In fact, all epigenetic inheritance we know of is under the control of the genome, the most important case being the cellular inheritance required to
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