When these mice bred, they gave birth to pups that started off with a slightly impoverished microbiome. And if those pups ate more low-fibre food too, even more microbes fell off the radar. As the generations ticked by, more and more old friends broke contact. This could explain why Westerners carry a much lower diversity of gut microbes than rural villagers from Burkina Faso, Malawi, and Venezuela.29 We not only eat fewer plants, we also heavily process the ones we do eat.