Arcanum Unbounded: The Cosmere Collection

by Brandon Sanderson

It is one of only two places in the cosmere where humankind does not predate the arrival of Shards.

I maintain, however, that the one of these with the largest potential impact on the cosmere is Hemalurgy. Usable by anyone with the right knowledge, this dangerous creation has proven able to warp souls regardless of planet or Investiture, creating false Connections that no Shard designed or intended.

Rosharan system can rival it, and there one of the planets is inhabited solely by Splinters.