December 23. At 8:15 P.M.—first operation in Europe according to Prof. Preobrazhensky : Sharik’s testes removed under chloroform anesthesia and replaced by graft of human testes with epididymis and seminal cords, obtained from a man of twenty-eight who died four hours and four minutes before the operation and preserved in sterile physiological fluid according to Prof. Preobrazhensky. Directly following, pituitary gland, or hypophysis, removed after trepanning of skull and replaced by a human one taken from above man. Expended : 8 cubes of chloroform, 1 syringe of camphor, 2 syringes of
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