Varadharajan Chandran

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Since the mitochondria were derived from the donor, the maternal mitochondrial genes were intact, and the babies born would no longer carry the maternal mutations. Humans born from this procedure thus have three parents. The fertilized nucleus, formed by the union of the “mother” and “father” (parents 1 and 2), contributes virtually all the genetic material. The third parent—i.e., the egg donor—contributes only mitochondria, and the mitochondrial genes. In 2015, after a protracted national debate, Britain legalized the procedure, and the first cohorts of “three-parent children” are now being ...more
The Gene: An Intimate History
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