Late in his twenties he was diagnosed with Addison’s disease, a deterioration of the adrenal glands that can trigger symptoms including fatigue, dizziness, muscle weakness, weight loss, difficulty standing up, nausea, sweating, and changes in personality and mood. He remained underweight well into adulthood. Navy doctor Lee Mandel, who examined Kennedy’s medical records years after Kennedy’s death, speculated that Kennedy’s Addison’s disease was probably caused by a rare condition, called autoimmune polyendocrine syndrome type 2, or APS 2, which also likely caused Kennedy’s hypothyroidism,
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