In cases where people seem to neglect the risks of worst-case outcomes, helping to prevent these outcomes might be a particularly effective altruistic activity. This is what the Skoll Global Threats Fund focuses on, trying to reduce the chances of global catastrophes arising from climate change, pandemics, and the proliferation of nuclear weapons. The charity evaluator GiveWell is currently investigating these sorts of activities in an attempt to work out how effective donations in these areas can be.