To add the importance of development, Gilbert and his colleagues use the term “symbiopoiesis,” the codevelopment of the holobiont. The term contrasts their findings with an earlier focus on life as internally self-organizing systems, self-formed through “autopoiesis.” “More and more,” they write, “symbiosis appears to be the ‘rule,’ not the exception…. Nature may be selecting ‘relationships’ rather than individuals or genomes.”