Vicky Chijwani

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mitochondrial genes can respond to local changes in conditions, modulating the membrane potential within modest bounds before changes become catastrophic. If these genes were moved to the nucleus, the hypothesis is simply that the mitochondria would lose control over the membrane potential within minutes of any serious changes in oxygen tension or substrate availability, or free-radical leak, and the cell would die.
The Vital Question: Why is life the way it is?
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