In science, it is important to limit two kinds of errors: false positives, where you conclude there is an effect when there isn’t, and false negatives, where you fail to notice a real effect. In some sense, false positives and false negatives are flip sides of the same coin. If we’re too ready to jump to conclusions about effects, we’re prone to get false positives; if we’re too conservative, we’ll err on the side of false negatives.