Two parts of the brain in particular are to blame: the prefrontal cortex and the limbic system. To simplify, the prefrontal cortex is basically the thinking part of the brain, and the limbic system is the feeling part. In depression, something is off with the way these regions act and communicate with each other. The thinking prefrontal cortex is supposed to help regulate the feeling limbic system, but it’s not doing a good job. Fortunately, it’s possible to change the way they act and communicate, and that’s what this book is all about.
