You now know dozens of ways to modulate all the important circuits. You can change dopamine and the dorsal striatum with exercise. You can boost serotonin with a massage. You can make decisions and set goals to activate the ventromedial prefrontal cortex. You can reduce amygdala activity with a hug and increase anterior cingulate activity with gratitude. You can enhance prefrontal norepinephrine with sleep. The list goes on and on, and these benefits create a feedback loop that causes even more positive changes.