Worrying and anxiety are distinct but related concepts—you can have worrying without anxiety and anxiety without worrying.6 Worrying is mostly thought based, whereas anxiety has more to do with physical components like bodily sensations (such as an upset stomach) or associated actions (like avoiding a situation). Worrying involves the prefrontal cortex and its interactions with the limbic system, particularly the anterior cingulate, while anxiety involves only the limbic system, mostly interactions between the amygdala, hippocampus, and hypothalamus. In essence, worrying is thinking about a
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