The same is true of your brain. In depression, there’s nothing fundamentally wrong with the brain. It’s simply that the particular tuning of the neural circuits creates the tendency toward a pattern of depression. It has to do with the way the brain deals with stress, planning, habits, decision making, and a dozen other things—the dynamic interaction of all those circuits. And once the pattern starts to form, it causes dozens of tiny changes throughout the brain that create a downward spiral.
