However, the single largest problem is taking a prescription antibiotic; it is like dropping an atom bomb into this unique and vital community. Antibiotics indiscriminately kill everything in sight. Once this happens, your uniqueness is lost. As the microbe population reestablishes itself, you end up with a new set of players. Your original population that helped to keep you healthy and fight disease never returns to normal, and the new population opens the door to disease. This is why taking an antibiotic even once can damage your health for the remainder of your life.