Bob Matthews

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They had the use of their hands; they could draw pictures and perform many-page-long calculations on paper—calculations in which one records many complex intermediate results along the way, and then goes back, picks them up one by one, and combines them to get a final result; calculations that I cannot conceive of anyone doing in his head. By the early 1970s, Hawking’s hands were largely paralyzed; he could neither draw pictures nor write down equations. His research had to be done entirely in his head.
Black Holes & Time Warps: Einstein's Outrageous Legacy
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