The aim is not to create a brain simulation so detailed and accurate that one could use it to predict exactly what would have happened in the original brain if it had been subjected to a particular sequence of stimuli. Instead, the aim is to capture enough of the computationally functional properties of the brain to enable the resultant emulation to perform intellectual work. For this purpose, much of the messy biological detail of a real brain is irrelevant.
Well, that’s the issue with wetware (but sheesh, what a thing to call the actual substrate of the human mind).
