No doubt, there are some synthetic AI designs that are less safe than some neuromorphic designs. In expectation, however, it seems that neuromorphic designs are less safe. One ground for this is that imitation can substitute for understanding. To build something from the ground up one must usually have a reasonably good understanding of how the system will work. Such understanding may not be necessary to merely copy features of an existing system. Whole brain emulation relies on wholesale copying of biology, which may not require a comprehensive computational systems-level understanding of
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