condition has increased in frequency over the past forty years, from rare in the mid-twentieth century to 1 in 150 children in the twenty-first.9 Initial small samples have demonstrated improvement in autistic behaviors with gluten removal.10, 11 The most comprehensive clinical trials to date with formal measures of autistic behavior have demonstrated improvement with gluten elimination (sometimes combined with elimination of casein from dairy and a variety of different nutritional supplements).12, 13, 14
