healthy beige adipocytes release a signal called bone morphogenic protein, or BMP, to the bone cells. In response, the bone cells produce signaling substances called osteocalcin and osteoprotegerin that influence insulin activity and blood sugar levels. From brown fat to bone to the insulin-secreting pancreas to the control of blood sugar, the progression is clear: A healthy skeletal structure results in healthy function that can reduce the risk of many chronic diseases.