More on this book
Community
Kindle Notes & Highlights
But such social outrage should be accompanied by a measure of wonder and respect: without any central planner coordinating their actions, without any education at all, this itinerant underclass managed to conjure up an entire system for processing and sorting the waste generated by two million people.
Waste recycling—in the form of composting and manure spreading—played a crucial role in the explosive growth of medieval European towns. High-density collections of human beings, by definition, require significant energy inputs to be sustainable, starting with reliable supplies of food. The towns of the Middle Ages lacked highways and container ships to bring them sustenance, and so their population sizes were limited by the fecundity of the land around them.
All nucleated organisms generate excess calcium as a waste product. Since at least the Cambrian times, organisms have accumulated those calcium reserves, and put them to good use: building shells, teeth, skeletons. Your ability to walk upright is due to evolution’s knack for recycling its toxic waste.
If some rogue virus wiped out every single mammal on the planet, life on earth would proceed, largely unaffected by the loss. But if the bacteria disappeared overnight, all life on the planet would be extinguished within a matter of years.
No one died of stench in Victorian London. But tens of thousands died because the fear of stench blinded them to the true perils of the city, and drove them to implement a series of wrongheaded reforms that only made the crisis worse.
The history of knowledge conventionally focuses on breakthrough ideas and conceptual leaps. But the blind spots on the map, the dark continents of error and prejudice, carry their own mystery as well. How could so many intelligent people be so grievously wrong for such an extended period of time? How could they ignore so much overwhelming evidence that contradicted their most basic theories? These questions, too, deserve their own discipline—the sociology of error.
But epidemics create a kind of history from below: they can be world-changing, but the participants are almost inevitably ordinary folk, following their established routines, not thinking for a second about how their actions will be recorded for posterity. And of course, if they do recognize that they are living through a historical crisis, it’s often too late—because, like it or not, the primary way that ordinary people create this distinct genre of history is by dying.
As Stephen Jay Gould argued in his book Full House, it makes for good museum copy to talk about an Age of Dinosaurs or an Age of Man, but in reality it’s been one long Age of Bacteria on this planet since the days of the primordial soup. The rest of us are mere afterthoughts.
In other words, an accidental ingestion of a million Vibrio cholerae can produce a trillion new bacteria over the course of three or four days. The organism effectively converts the human body into a factory for multiplying itself a millionfold. And if the factory doesn’t survive longer than a few days, so be it. There’s usually another one nearby to colonize.
THE TRAGIC IRONY OF CHOLERA IS THAT THE DISEASE HAS A shockingly sensible and low-tech cure: water. Cholera victims who are given water and electrolytes via intravenous and oral therapies reliably survive the illness, to the point where numerous studies have deliberately infected volunteers with the disease to study its effects, knowing that the rehydration program will transform the disease into merely an uncomfortable bout of diarrhea.
Even with its higher crime rate, New York City in its debauched nadir of the 1970s was a vastly safer place to live than Victorian London. During the epidemics of the late 1840s and the 1850s, a thousand Londoners would typically die of cholera in a matter of weeks—in a city a quarter the size of present-day New York—and the deaths would barely warrant a headline.
For millennia, most cities had been bound inexorably to the natural ecosystem that lay outside their walls: the energy flowing through the fields and forests around them established a population ceiling they couldn’t grow beyond. London in 1854 had shot through those ceilings, because the land itself was being farmed more efficiently, because new forms of energy had been discovered, and because shipping and railway networks had greatly expanded the distance that energy could travel.
In a sense, the Industrial Revolution would have never happened if two distinct forms of energy had not been separated from the earth: coal and commoners.
Brewed tea possesses several crucial antibacterial properties that help ward off waterborne diseases: the tannic acid released in the steeping process kills off those bacteria that haven’t already perished during the boiling of the water. The explosion of tea drinking in the late 1700s was, from the bacteria’s point of view, a microbial holocaust.
With the exception of the earth’s atmosphere, the city is life’s largest footprint. And microbes are its smallest. As you zoom in past the scale of the bacterium and the virus, you travel from the regime of biology to the regime of chemistry: from organisms with a pattern of growth and development, life and death, to mere molecules.
Chadwick helped solidify, if not outright invent, an ensemble of categories that we now take for granted: that the state should directly engage in protecting the health and well-being of its citizens, particularly the poorest among them; that a centralized bureaucracy of experts can solve societal problems that free markets either exacerbate or ignore; that public-health issues often require massive state investment in infrastructure or prevention.
The first defining act of a modern, centralized public-health authority was to poison an entire urban population.
Whenever smart people cling to an outlandishly incorrect idea despite substantial evidence to the contrary, something interesting is at work.
In other words, methane and putrescine and cadaverine are the smoke. Microbes are the fire.
Our noses are far more adept than our eyes at perceiving the very small.
Snow knew that the case would be made in the exceptions to the rule. What he needed now were aberrations, deviations from the norm.
This is how great intellectual breakthroughs usually happen in practice. It is rarely the isolated genius having a eureka moment alone in the lab. Nor is it merely a question of building on precedent, of standing on the shoulders of giants, in Newton’s famous phrase. Great breakthroughs are closer to what happens in a flood plain: a dozen separate tributaries converge, and the rising waters lift the genius high enough that he or she can see around the conceptual obstructions of the age.
History has its epic thresholds where the world is transformed in a matter of minutes—a leader is assassinated, a volcano erupts, a constitution is ratified. But there are other, smaller, turning points that are no less important. A hundred disparate historical trends converge on a single, modest act—some unknown person unscrews the handle of a pump on a side street in a bustling city—and in the years and decades that follow, a thousand changes ripple out from that simple act. It’s not that the world is changed instantly; the change itself takes many years to become visible. But the change is
  
  ...more
Psychologists call this type of faulty reasoning “confirmation bias”: the tendency to force new information to fit one’s preconceptions about the world.
(Insulin, it turns out, remains stable for weeks at room temperature.)
outcome. Game theory has always had trouble accounting for players with no rational self-interest,

