Dan Seitz

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When the citizens of London and other great cities first began gathering together in such extraordinary number, when they began building elaborate mechanisms for storing and removing their waste, and pulling drinking water from their rivers, they did so with conscious awareness of their actions, with some clear strategy in mind. But they were entirely unaware of the impact that those decisions would have among the microbes: not just in making the bacteria more numerous, but also in transforming their very genetic code.
The Ghost Map: The Story of London's Most Terrifying Epidemic--and How It Changed Science, Cities, and the Modern World
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