More on this book
Community
Kindle Notes & Highlights
research revealed that frailty was the most powerful predictor of surgical outcomes,
Overall hospital lawsuits against patients dropped by 80%, a finding we documented in a follow-up JAMA article.
In nearly every research endeavor of my career, the idea we studied was not initially accepted within the profession. But then, eventually, it became accepted.
today’s medical culture crushes the creativity of Ben Franklin thinkers.
Ben Franklin would likely be stifled in academics today.
Most American adults take four or more prescription medications regularly, making the U.S. the most medicated population in the world.
“If you don’t believe in freedom of speech for people you disagree with, you don’t believe in freedom of speech at all.”
the modern medical establishment got so many major health recommendations wrong over the last few decades, it raises an unsettling question: What are we getting wrong today?
Many of today’s medical practices are not supported by good studies.
40% of accepted practices did not hold up when rigorously tested.
JAMA once told me that 60% of what we as physicians do in medicine is discretionary.
The medical profession should be funding studies to address these gaps, but it’s doing the opposite.
research today is concentrated in the pharmaceutical space because that’s where funding is abundant.
Studies that lead to a drug’s approval are rarely repeated—for fear they might not yield ...
This highlight has been truncated due to consecutive passage length restrictions.
we spend billions on new drugs and blood tests, but very little to study how food affects body inflammation, nutrition, and the microbiome.
two dentists I trust the most both use toothpaste without fluoride and have expensive systems in their homes to defluoridate their water.
the data to support fluoride in drinking water to prevent cavities is flimsier than people realize.
Most studies were done before 1975 and had study-design issues. In addition, the studies did not consider the increasingly common use of fluoride toothpaste
countries that have not added fluoride in their drinking water have also seen reduced cavity rates.
know for certain is that if someone tells you that fluoridation of the water supply is entirely safe and essential for public health, that is an opinion, not a fact.
marijuana use increases the risk of heart attack and stroke—a 25% and 42% increase respectively, according to a 2024 study published in JAMA.
80% of marijuana sold in the U.S. is grown illegally14 by cartels and Chinese organized crime groups operating large farms in places like California, Oklahoma, and Kentucky.
Humboldt County, California, a mecca of illegal marijuana farms, has one of the highest rates of murder and missing persons in the state.
studies have suggested that treating fevers may prolong illness.
That’s because fevers are the body’s way of naturally fighting an infection.
studies have similarly shown that infections last longer when a fever is lowered with medications like Tylenol.
elevated body temperature may help fight off some bacteria and viruses or bolster the immune system; both mechanisms are suggested in the medical literature.
before the era of antibiotics, doctors induced fevers in people in an attempt to fight off infections.
(Acetaminophen) Use in Infants and Children Was Never Shown to Be Safe for Neurodevelopment.”
one large study, 58% of people informed by the Galleri test that they might have cancer ended up having nothing.
the test may miss up to 70% of cancers.
Current enthusiasm for mRNA vaccines within the scientific community means that new vaccines that use traditional technology don’t get as much funding and support.
There’s also another big reason why there may not be a rush to develop this. Pharma can’t make billions on it.
TRT should not be regarded as the male equivalent of HRT.
TRT has been alleged to cause prostate cancer, an allegation that has not been well supported in studies.
71% of children who took puberty blockers had no improvement in their mental health and about one third did worse.
cases of youth identifying as transgender occurred in clusters rather than randomly in the population, and many had underlying mental health disorders.
lactation consultants, dentists, and pediatricians are recommending cutting the base of the tongue
There’s not good evidence to support the procedure.
Muscle mass is the leading predictor of longevity. Loss of muscle mass is a component of the frailty syndrome.
the data supporting the most recent broadening of mammogram recommendations are strikingly flimsy.
COURAGE trial66 revealed that heart stents have zero impact on prolonging one’s life,
Stents can alleviate angina (chronic chest discomfort) symptoms, but they don’t extend patients’ lives.
stents disrupt the lining of the inside of the blood vessel and can cause a blockage—a
