It was an orphan disease, with only four recorded cases having occurred throughout history. The circumstances of each patient were similar: They had congenital deficiencies in the endocrine and nervous systems. When disrupted, their personality would drastically change. Usually, they were numb to pain, but when their condition flared up, they would lose touch with reality, become bloodthirsty, and gain intense destructive tendencies toward themselves or others, resulting in a standard antisocial personality. Physical symptoms included a high fever and confusion, with each flare-up being more
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