The DNA of the nucleus is especially vulnerable when a cell is dividing, during which time the DNA strand is literally unwound and stretched out. Researchers are now able to confirm not only that free radicals can damage the DNA nucleus of a cell, but also which strands of the DNA they damage most frequently. When met with an onslaught of carcinogens, the body’s MASH unit will be busy trying to repair the damaged DNA. But in times of heavy oxidative stress, free-radical damage overwhelms the repair system and can lead to mutation of the DNA. Free radicals can also wreak damage on the genetic
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