A major affective disorder is essentially a biochemical disease. In other words, something has gone awry with the neurohormones, the chemicals that relay messages among the brain cells. The biochemical changes may be the result of severe stress to the system or may be due to genetic factors. The symptoms of clinical depression have a fairly well-defined beginning. The person previously enjoyed life, was active, and had interests until some particular time when things began to change. Sometimes the change can be related to a physical event such as childbirth, menopause, surgery, or a severe
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What depression is and how its diagnosed and some causes
