The claims of too many laboratory-based doctors to the contrary, medicine will always remain, as the ancient Greeks first dubbed it, an Art. One of the most severe demands that its artistry makes of the physician is that he or she become familiar with the poorly delineated boundary zones between categories of treatment whose chances of success may be classified as certain, probable, possible, or unreasonable. Those unchartable spaces between the probable and everything beyond it are where the thoughtful physician must often wander, with only the accumulated judgment of a life’s experiences to
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