had a similar, if much milder, epiphany when in my midforties I was prescribed a serotonin-enhancing antidepressant. I was suffused by a sense of well-being I’d never imagined was possible. It was as if my brain cells were bathed in a normal chemical milieu for the first time. “So this is how human beings are meant to feel,” I remarked to my sister-in-law. You don’t know how depressed you’ve been until you know what it feels like not to be depressed.