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(BSL-4) laboratory, a new sort of facility since Karl Johnson’s early work (and of which he was one of the pioneering designers), with multiple seals, negative air pressure, elaborate filters, and lab personnel working in space suits—a containment zone in which Ebola virus could be handled without risk (theoretically) of accidental release. No one knew whether any of these Zairian spleens contained the virus but each had to be treated as though it did. From the spleen material, minced finely and added to cell cultures, the lab people tried to grow the virus.
Spillover: Animal Infections and the Next Human Pandemic
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