Spillover: Animal Infections and the Next Human Pandemic
Rate it:
Open Preview
Kindle Notes & Highlights
2%
Flag icon
It’s a word of the future, destined for heavy use in the twenty-first century.
2%
Flag icon
about 60 percent of all human infectious diseases currently known either cross routinely or have recently crossed between other animals and
2%
Flag icon
By the cold Darwinian logic of natural selection, evolution codifies happenstance into strategy.
2%
Flag icon
Ecological disturbance causes diseases to emerge. Shake a tree, and things fall out.
9%
Flag icon
Any such spillover in the reverse direction—from humans to a nonhuman species—is known as an anthroponosis.
38%
Flag icon
Because viruses are vanishingly minuscule, simple but ingenious, anomalous, economical, and in some cases fiendishly subtle.
39%
Flag icon
Darwinian natural selection. They evolve. The viruses on Earth today are well fit for what they do because only the fittest have survived.
44%
Flag icon
Evolution lowers virulence, tending toward that “more perfect mutual tolerance” between pathogen and host.
45%
Flag icon
In reality the virulence of a parasite “is usually coupled with the transmission rate and with the time taken to recover by those hosts for whom the infection is not lethal.”
46%
Flag icon
It’s sort of a chicken-and-egg problem, he said. RNA viruses are limited to small genomes because their mutation rates are so high, and their mutation rates are so high because they’re limited to small genomes. In fact, there’s a fancy name for that bind: Eigen’s paradox.
51%
Flag icon
They don’t come after us. In one way or another, we go to them.