1. Shine a spotlight on a problem or opportunity 2. Pay only for results 3. Target an ambitious goal without predicting which team or approach is most likely to succeed 4. Reach beyond usual suspects to tap top talent 5. Stimulate private-sector investment many times greater than the prize purse 6. Bring out-of-discipline perspectives to bear 7. Inspire risk taking by offering a level playing field 8. Establish clear target metrics and validation protocols