Another recent study, this one from Massachusetts General Hospital, funded by the National Institutes of Health and the National Science Foundation and published in a March 2012 issue of the journal Science, also shows a regular structure of connections across the neocortex.5 The article describes the wiring of the neocortex as following a grid pattern, like orderly city streets: “Basically, the overall structure of the brain ends up resembling Manhattan, where you have a 2-D plan of streets and a third axis, an elevator going in the third dimension,” wrote Van J. Wedeen, a Harvard
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