Form ions of a vaporous uranium compound and start them moving at one side of a vacuum tank permeated by a strong magnetic field and the moving ions as they curved around would separate into two beams. Lighter U235 atoms would follow a narrower arc than heavier U238 atoms; across a four-foot semicircle the separation might be about three-tenths of an inch. Set a collecting pocket at the point where the U235 ion beam separately arrived and you could catch the ions.