Self-transcendence is among the central features of spiritual experience, and it turns out that the loss of self has a neural signature. There is a set of linked structures in the brain that are more active whenever we are processing events from an egocentric point of view—thinking about what I want, what I need to do next, or what other people think of me. These brain structures are so often active together that they are collectively called the default mode network (DMN), meaning it is what the brain is usually doing, except in the special times when it is not.[17]
