Shortly thereafter, my lab conducted some experiments looking at HFCS and sucrose. We found in our lab rats that those who were given HFCS to drink gained significantly more body weight than rats given equal access to a sucrose solution, even though they consumed the same number of total calories. We also looked at the long-term effects of HFCS on body weight and some parameters related to obesity and metabolic health. Over the course of six or seven months, both male and female rats with access to HFCS gained significantly more body weight than the control groups. This increase in body weight
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