Luce and her husband, Henry, publisher of Time and Life, two of the most influential magazines in the world at the time, were staunch Republicans and anti-Communists who supported the CIA and its covert operations. They were also ardent proponents of psychedelic therapy, especially Clare, who had used LSD to cope with the death of her daughter and had introduced it to many of her friends and associates. Their personal beliefs influenced a series of largely positive articles on psychedelics that appeared in Time and Life throughout the late 1950s and into the early 1960s.

