If you accept Daniel Deudney’s argument that a large human presence in space gives us a lot of power to destroy ourselves, you should think twice about creating settlements where you anticipate the culture will place a low value on human life.
How did they jump to the conclusion that space settlers would have low value for human life? Jumped to the conclusion that there will be higher incidence of disability, so the society would not take care of them, so the society doesn’t value human life, so all space settle communities wold not value human life. Idiotic.