If you do have to compare your drug with one produced by a competitor—to save face, or because a regulator demands it—you could try a sneaky underhand trick: use an inadequate dose of the competing drug, so that patients on it don’t do very well; or give a very high dose of the competing drug, so that patients experience lots of side-effects; or give the competing drug in the wrong way (perhaps orally when it should be intravenous, and hope most readers don’t notice); or you could increase the dose of the competing drug much too quickly, so that the patients taking it get worse side-effects.
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