I mainly picked this up for research on an upcoming project. I was looking for a more historical/archeological book but this is more chemistry/biological based. Not a bad thing, but not exactly what I was looking for.
This book, as a whole, is good and largely enjoyable to read, but there are a couple of caveats for readers, especially if they're coming to this book as wine-enthusiasts rather than scientists (or both). First, this book is written by two scientists that happen to be wine lovers and not by two wine lovers who happen to be scientists. Yes, there is a difference.
There are several chapters that lend themselves to in-depth treatments of the science behind the subject, and it's obvious that the two authors are in their element here. Unfortunately, while their discussions of the chemical structures of sugar and alcohol, the chemistry behind photosynthesis and fermentation and the role of the ventral putamen in pleasure-processing (to name but a few) are interesting at one level, they quickly get lost in minutiae at another.
This gets especially bad for anything involving molecules and chemistry, and the final experience for me of reading any of those chapters was a steady shift from really wanting to figure the science out to feeling ignorant and guilty for not paying enough attention during 10th grade Chemistry. I suppose it's possible that I deserve to feel ignorant and guilty, and there is a little part of me that wants to go dust off my Intro to Chem and Bio textbooks (of course I saved them, didn't you?) and review this stuff until I understand what they were talking about, but the reality is I won't actually be doing that, so I'm just left with the guilt and ignorance.
Second, they give short shrift to a surprising amount of the history of wine. Yes, the first chapter does try to situate wine in a historical context, but after they get past the Romans they seem to run out of steam, and the next thing you know it's the 19th century. An attention to history reasserts itself in the chapter on Phylloxera as well as here and there throughout the book, but the overall effect is that this is less a history of wine (or even a "natural history" of wine) written for someone new to the subject than a supplement for someone already versed in the broad sweep of that history and looking for some new insights and perspectives. All of that said, this was still a terrific read. Though I slogged through some of the technical stuff, the writing was generally engaging and their approach to a couple of key issues was fresh and interesting (I especially recommend the chapters on Wine and Technology and Climate Change).
The book itself is gorgeous, beautifully composed and illustrated. I recommend this book to anyone who already has even a just a little background or experience with wine, as you are sure to get something out of it, and if you hit an overly technical patch, just skip over it. To a wine enthusiast with a science background (especially in chemistry), I recommend the book unreservedly. As a first introduction to wine, though, a different book might be a better place to start.