This book was good, but it didn't quite deliver on the parameters set by the author. This is the first book by Wills I've read, but I don't get the impression that he is as much a "critic" as he is a historian. He is never far from the page, and eager to jump into his story. This book is also very populated with Henry Adams, who Wills would publish a book on in 2005. These aren't knocks on the book, per se, just an important caveat, that you are coming to this for a very personal, verging on pedantic at times take on history.
Jefferson gets a beating here, and deservedly so, that's what I wanted out of the book, but he is so often absent from the page. I also wanted to know more about him and his policies, rather than just about his enemies. I think that employing Timothy Pickering (a figure I had never heard of) as the mouth piece for the anti-Jefferson arguments of the books works pretty well, but by the end of the book there is nearly 50 pages chronically John Quincy Adams career in the House, because he had been Pickering's rival 25 years earlier, I guess. It isn't completely misplaced in the book, but seems to suddenly be much less about Jefferson, and about the "slave power" in a very different way than the first 2/3 of the book.
If you are familiar with and enjoy Wills history writing, this is a good one I think. If you don't know much about Jefferson and want to know more, this isn't a good starting point, but it is on the shelf or the list and is an important entry.