I've sat, trying to think of how to review this book, and come up short. Every description fails to capture the experience I had when listening to The Epiphany Machine--and I highly recommend the audio version of this novel, with excellent narration by Ari Fliakos--and I'm not surprised to see that other reviews seem to have missed the point, missed the experience entirely. For those looking to see neat answers, tidied threads snipped off and packaged for the reader, this is not the book for you. For those looking to take a deeper look into humanity, into self-knowledge and what that means and how we might achieve it, and accompany a protagonist who is beautifully flawed and therefore the epitome of humanity itself in its self-loathing and regret, this is the novel you need.
I wasn't sure where to shelve this, as it says it's science fiction, but it isn't. Not really. Which is part of the reason I love it. There are fantastical elements but the book, the characters, the dirty apartments and the streets of New York, are grounded and do not let you fool yourself into thinking this could never happen. So much of it did. But if you're looking for a space odyssey or an alternate universe, this is not the book for you.
Stylistically, the interwoven narratives, interviews, selections from fiction within a fiction worked for me; if someone has trouble following anything other than a perfectly linear narrative, then this is not the book for you. But nothing about it was ever hard to follow: interviews are labeled with dates and peppered with references that make it easy to know exactly who is speaking, and when, and the storyline itself has a natural progression that never confused me or left me behind.
If you're looking for a book that refuses easy categorization, other than to be labeled as the best book I read in 2020, then this is the book for you.