Format: Hard-cover
This book shows that it pays to be bold and take risks in academia, just as in business.
A life decoded was a great story about an adventurous life, was educational in terms of what the science actually did, and provided key insights on how politics in academia operate.
Fantastic book.
I also really enjoyed the quotes at the start of each chapter, usually from Darwin.
Some memorable quotes all throughout the book:
p125: "In science the credit goes to the man who convinces the world, not to the man to whom the idea first occurs. Not the man who finds a grain of new and precious quality but to him who sows it, reaps it, grinds it and feeds the world on it" - Sir Francis Darwin, First Galton Lecture before the Eugenics Society (1914)
p148: "Son, you are obviously doing extremely well." He did not strike me as being au fait with the science, so I asked him why my success was so obvious: "This is Washington, and we judge people by the quality of their enemies, and son, you have some of the best." - Narration
p159: "Let me tell you the secret that has led me to my goal. My strength lies solely in my tenacity" - Louis Pasteur (1822-1895)
p189: If you cannot - in the long run - tell everyone what you have been doing, your doing has been worthless. - Erwin Shrodinger, 1933 Nobel Prize winner in Physics
p251: The public genome people assumed the fort to sequence an genome was too sizeable for a single laboratory. As mentioned earlier, the yeast genome, which was only about three times the size of Haemophilus influenza, had required some one thousand "monks" working for almost ten yard in laboratories spread all over the world. The problem with that approach was that while a few centres did high-quality work, many others were of only average quality or even worse. The first yeast chromosome sequence to be published had to be redone, under-scoring the management issues in having each diverse lab trying to read code in its own way, with varying degrees of success. In this system, quantity of sequence, not quality, was what mattered most. - Narration
p254: A man cannot be too careful in the choice of his enemies.
- Oscar Wilde: A Picture of Dorian Grey
p260: The battles went all the way to the Applera board, where I had to argue my case for filing patents only when there was clear value. I was fighting for my integrity and that of my team because we had promised to make the human genome publicly available. The stress was more than I could handle at times. By then I had gotten to know Bill Clinton a little and was inspired by the way he dealt with the endless pressures from the job, the media, and his political opponents. Not letting your opponents see you cringe and sweat can be more damaging to your attackers than a good counterpunch (though the later can be very satisfying).
- Narration
p309: Then I received a copy of Tony Blair's speech, and my blood began to boil. Drafted by his chief scientist, Sir Bob May, it was so partisan that I suspected the Wellcome Trust had had a major influence on its drafting.
I was so upset that I called Ari and told him that if Blair went ahead with those remarks, I would boycott the White House ceremony and hold my own press conference. Ari tried to calm me and promised to call Neal Lane immediately. He told me not do anything rash -- in fact, not to do anything or call anybody until I heard back from him or Neal. Neal finally called and wanted to go through Blair's speech with me, line by line, to clarify what had offended me. When I finished, he clearly understood my position and was sympathetic, but he said there was little he could do. "I can change anything you want in Collins's speech and even the president's, but you re asking me to change a major international address by a foreign head of state. I just can't do that."
The lack of reassurance reminded me of Collins's prevarication in our basement discussions when he told me, as Lander had done before him, that he could not speak for his colleagues. Collins had also said he had nothing to do with the release of the ultimatum letter to the L.A. Times and ha blamed the Wellcome Trust. If someone deceives me once, then shame on him; it if happens twice, then shame on me. I was not going to let it happen a second time on live television from the White House. I was firm: If the speech went out as it was, I would not show up. Neal pleaded with me to wait until he had at least tried to get it changed.
Being an optimist I kept working on my text and sitting at the computer in my home office after midnight when my phone rang. It was a relieved-sounding Neal Lane, who assured me that everyone had gotten my message and that Tony Blair's speech would be rewritten. Could I see a copy first? I had his assurances that the speech would be changed and that I would be pleased. Now would I agree to participate? I had never known Neal to be anything less than honourable and straightforward, so I accepted his word. The conversation quickly turned to my speech. I promised him a copy by 6:00 A.M. but walked him through what I wanted to say. Neal seemed pleased. The next time we would see each other would be at the White House in the morning. We were going to unveil the book of humankind to the world.
p311: The next day Collins phoned to plead with me, saying it would end the wrong message to have only one of us appear on the cover, and I reluctantly agreed. When I told Dick Thompson, he asked if I was really sure. I said I was feeling magnanimous an it was the right thing to do.
p320: A scientific man ought to have no wishes, no affectations - a mere heart of stone -- Charles Darwin