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Resistant (Dr. Lou Welcome, #3)
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(Dr. Lou Welcome #3)

3.85  ·  Rating details ·  2,265 ratings  ·  254 reviews
They fight without conscience or remorse. Their only job is to kill.
They are the most ruthless enemy we have ever faced.
And they are one millionth our size.
When Dr. Lou Welcome fills in last minute for his boss at a national conference in Atlanta he brings along his best friend, Cap Duncan. But an accident turns tragic when Cap injures his leg while running. Surgeons
Hardcover, 387 pages
Published May 20th 2014 by St. Martin's Press
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Daniel Palmer Hi, that's a work of my dad's imagination. Pretty believable though, right?
Daniel Palmer Hi Gary...sorry, just saw this! :) The answer is YES. Flesh eating bacteria is currently a problem and terrorists would love to get their hands on an…moreHi Gary...sorry, just saw this! :) The answer is YES. Flesh eating bacteria is currently a problem and terrorists would love to get their hands on an effective biological weapon. Here's a link to the 10 scariest bio weapons I found. Hmmm...I think the weapon in RESISTANT might be scarier. Thanks for giving the book a read. (less)

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Average rating 3.85  · 
Rating details
 ·  2,265 ratings  ·  254 reviews

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Mary Beth *Traveling Sister*
I really liked this series until I read this book, which I think is the last book in the series. The character development in this series, I feel wasn't done so well. I have loved every book by Michael Palmer and loved every book that he wrote until I read this one. I did enjoy certain parts but it seemed to drag when they discussed the topic of bacteria. It at one point felt to me that it was nonfiction dragging the topic of bacteria. Some parts just felt like it was over my head. This book was ...more
Oct 04, 2015 rated it liked it

3.5 stars

in this 3rd book in the 'Dr. Lou Welcome' series, Dr. Welcome is in a race against time to find a cure for a horrific man-made microbe. The book can be read as a standalone.


An organization called the "Society of One Hundred Neighbors", which has exactly 100 members, wants to control the U.S government so they can get rid of policies they don't like - especially entitlement programs. The society has secret members across the country including politicians, cops, judges, doctors,
Jan 15, 2014 rated it it was amazing
Dr. Lou Welcome is a recovering drug and alcohol addict who is now an ER doc in D.C. His best friend and sponsor, Cap, is a longtime friend who has helped him through the worst times of his life. While Lou and Cap are at a medical conference in Atlanta they decide to go trail running. When Cap is hurt during the run Lou draws upon all of his medical experience to try to save him. After safely getting Cap to the hospital and on his way to recovery Lou must go back to D.C. to try to save his job. ...more
Aug 03, 2015 rated it liked it
Shelves: medical-fiction
Having not read Michael Palmer before i saw this in the library give it a go was okay but not outstanding the story starts when a scientist working on the centres top secret case is kidnapped by terrorists Dr Lou Welcome is on the hunt that takes him from hospital wards to the top corridors of power as he races against time to stop a lethal epidemic to the world & races to save his best friend Cap who has a germ eating flesh which may kill him would read more of this author
Jun 10, 2014 rated it did not like it
Maybe it's my fault - I thought this would be a good summertime read, another enjoyable "end-of-the-world-as-we-know-it" apocalypse story, but I was soooo wrong. It was just cheap, political propaganda, and I resent the author's intent to vilify me as a domestic terrorist just because I sustain and support the Constitution. I was extremely disappointed in this novel.
Ray Palen
May 01, 2014 rated it really liked it
It is bittersweet to have to review a novel by one of my favorite authors that was released posthumously. RESISTANT is the final novel written by the great Michael Palmer who died unexpectedly last fall

For decades, Palmer established himself as a top-notch writer of primarily medical thrillers. One of his novels even made it to the big screen as EXTREME MEASURES was made into a film starring Hugh Grant and Harrison Ford. Palmer's last few novels went away from the medical genre and were solid
Jun 18, 2014 rated it did not like it  ·  review of another edition
First off let us get a couple of things on the table, I don't consider myself to be a high brow reader, what I look for in books is entertainment, pure and simple, anything else that comes along is surely welcome and well recieved.
With that out of the way I'd sincerely recommend anyone to avoid this book like the plague.
It starts off well enough, we are introduced to the bacteria, a very nasty piece of work that is unstoppable. This evil thing was released into the world by a group of
May 11, 2014 rated it liked it
It has been a few books since I have read anything by Mr. Palmer. His latest and last one sounded like a winner. I am sorry that I did not read more of his books while he was alive. This book was a good, quick read. The idea of a bacterial flesh-eating virus is scary. So scary that I was talking to my co-worker about this book and told her that if this ever happened to me that I would just want to be put out of my misery. I would not want the doctors cutting of my limbs one at a time.

So the
Jan 25, 2018 rated it really liked it
I had no idea this was a series-so this read just fine as a standalone book. Dealing with deadly germs-it's certainly a relevant topic to what is going on in the world. Parts are very fast paced. Great character development with a fascinating array of people. Interesting read.
Nov 25, 2019 rated it really liked it
Gripping thriller, well paced and in its own way, terrifying.
Michael Adamchuk
A novel about an out of control resistant designer bacteria, an extremist group, pharma and politics. Pretty good story.
Jul 26, 2019 rated it really liked it
Have not read the two books before it, but I enjoyed this one. End of the world thriller. Short and easy. Will try the other two books.
Benjamin Thomas
Medical thrillers seem to come and go and often, after completing my reading of them, I tend to toss them aside, grateful for the opportunity to get to a really good book. I’ve even done that with a Michael Palmer book or two in the past. But I’m happy to report that this series of books featuring Dr. Lou Welcome is probably Palmer’s best work.

The plot for this novel sounds, at first glance, extremely hokey…something reminiscent of a movie-of-the-week from back in the 70’s. A group of 100
Tom Duff
Aug 17, 2014 rated it really liked it  ·  review of another edition
Michael Palmer

I'm sad that Resistant by Michael Palmer is the last episode of Dr. Lou Welcome that I'll ever have the pleasure of reading. Palmer passed away as the book was being finished, so this will serve as his final work. I read that his family worked to finish it up and get it published, and I wonder if that's responsible for a few of the nagging issues I had with the story.

The overall story line involves the emergence of a bacteria that is resistant to all antibiotics that
Apr 26, 2014 rated it liked it
3.5 out of 5 stars - "It is not our nature to suffer, and most of those who are offered government handouts in place of effort will take them."

My reaction to this third book in the Dr. Lou Welcome series probably was a bit affected by the fact that I had just finished watching Part I and Part II of ATLAS SHRUGGED (author: Ayn Rand) on Netflix. Both have a theme centering on political philosophy: the 100 Neighbors in RESISTANT want the government to end entitlement programs such as Social
Dr. Lou Welcome is sent to Atlanta to give a presentation for his boss. It is to take place at a medical conference where Lou's boss dreams of becoming the president. He wanted to give the talk himself but his wife's ill health forced him to remain at home.

Lou brings his best friend and AA sponsor Cap Duncan. They go running on mountain terrain and a fall lands Cap in the hospital. While there, he contracts a deadly infection for which there is no cure. This flesh eating bacteria is dubbed the
Scott Parsons
Jan 25, 2015 rated it really liked it
Shelves: thriller, politics
When starting this review, I was disappointed to learn that Michael Palmer had died in October 2013. Although some reviewers whine that this novel was published posthumously so somebody or bodies finished it, I found it to be a thoroughly enjoyable medical/quasi-political thriller. The flesh-eating "Doomsday Germ", as the media term it, was released into some hospitals by a political organization called 100 Neighbors whose mission is to roll back what Tea Party types call "the welfare state." ...more
Dan Curnutt
Apr 07, 2014 rated it it was amazing
Michael Palmer gives us another Medical drama / action thriller that is amazing. He takes four or more different sub-plots about one bacterial infection and weaves them together in an unforgettable novel.

What would happen if 100 ultra rich and powerful people in the United States formed a secret society that was set on bringing our Government to it's needs and forcing it to close down all social programs, such as Social Security, Medicare, Food Stamps, etc. What would happen. Well this group
Feb 06, 2017 rated it really liked it  ·  review of another edition
Shelves: 2017, audio-books
Listening to the audio version of Resistant was very enjoyable by Michael but probably not for the reason that you would think. I have been a fan for many years and then for some reason had stopped reading his books. What did not work for me in this story was the group of characters of the far right extremists named 100 Neighbors. They were just too pure evil. I would have liked to have heard some redeeming quality about that group. Their goal was to get "entitlements", Medicare and Social ...more
Debbie Oxier
Jan 22, 2015 rated it liked it
Normally I love Michael Palmer's books but for some reason this one fell short. I got bogged down a couple of times and found myself skipping a few pages. It wasn't the main character. I really liked Dr. Lou Welcome with all his faults and weaknesses. He had gotten hooked on amphetamines and ended up in rehab, his life in shambles. Now he's reestablished a relationship with his daughter and is getting along much better with his ex-wife. He even has a job in the medical field, helping others with ...more
Nov 11, 2015 rated it liked it
I really did enjoy much of Michael Palmer's earlier works (he was neck-and-neck with Robin Cook for a while), and I was sorry to hear this was his last book.

That being said, the plot twists and turns (from the trail run, to the CDC, to the FBI investigation, to Red Cliffs) and the persistent amazing-ness of Dr. Lou Welcome went from pretty cool to overbearing and then just plain ridiculous. As the story went on, I started thinking of the Old Spice Guy from recent TV commercials. From Wikipedia:
Jun 01, 2014 rated it liked it
As much as I enjoy Michael Palmer's novels, I am not a fan of Dr. Lou Welcome. As this book was released after Palmer's unexpected death, I wanted to like it and tried to keep a more open mind about Welcome. Truthfully, I didn't find him quite as irritating, and the premise of the medical portion of the book was interesting. The resolution was tense and shocking....all makings of a good thriller. As great a guy as "Cap" may be, I was kind of tired of reading the same descriptions of the man, and ...more
Apr 18, 2014 rated it it was ok
I won this book as a First Reads giveway through Goodreads. This book had such a cool premise yet the writing brought this down to a 2 star book. There was barely any character development. Characters would pop up without an explanation of who they were for another 20 pages. There is one line in the book where it is thrown out that the guy's daughter has a cat. So????

The main character depises other doctors for not being emphathetic yet in his mind he apparently can connect with people like no
Dec 27, 2014 rated it really liked it
I was saddened to hear of Michael Palmer's death in 2013, so this is the last of his writing which will be published.

It was a pretty good thriller, involving a so-called Doomsday Virus, which was actually a bacterium since it was first treatable with antibiotics. Then the bacterium mutated, and scientists were frantically looking for something that would destroy it, since the incidence of the human cases were spreading. Unknown to the government and the doctors trying to treat patients, the
Tom Tischler
Nov 07, 2014 rated it it was amazing  ·  review of another edition
When Dr. Lou Welcome fills in as a last minute replacement for
his boss at a convention in Atlanta he brings along his best
friend Cap Duncan. An accident turns tragic when Cap injuries his
leg while running. Surgeons save the leg but the open wound is a
perfect breeding ground for a deadly microbial invader committed
to eating Cap alive from the inside out. The germ is resistant to
any known antibiotic and the scientist tasked with finding a cure
has been kidnapped. Turning to the Center for Disease
I like the main character in this book - he's the reason I picked this one up at the library. I enjoyed the story but parts of it were definitely far-fetched. I don't think an FBI agent would be wounded would be allowed to join the hunt for the person who shot him. Especially if the shooter also shot someone the agent loved.

The 100 Neighbors is an interesting departure from the usual types of villains. Lately everyone's villains seem to be some type of Muslim extremist. But this group is a
Based on the book's blurb and the couple of chapters I had read in advance of my vacation, I brought this book along with me expecting a entertaining and thrilling read as I had come to expect from Michael Palmer.

Unfortunately, the cringe worthy character descriptions and dialogue and blatant political positioning totally through me off, and honestly made it very difficult for me to finish this book. Can't say I'm not just a little disappointed.

Thank you to Goodreads First Reads for providing me
Fredrick Danysh
Jan 14, 2017 rated it really liked it  ·  review of another edition
A domestic terror group has released a flesh eating virus in American hospitals in order to force the government to cancel all entitlement programs. While the deaths pile up, Dr. Lou Welcome and Cap who is both his friend and addiction rehab sponsor are in Georgia when Cap breaks his leg and contracts the virus. A race to find an antidote for the out of control mutations of the virus between the terrorist and the government grows as deaths increase. This is a fast paced thriller.
Dec 01, 2014 rated it really liked it
I hadn't read anything by the author before so I really didn't know what I was in for when I decided to read (i.e. listen to the audio book). I found the premise of the book to be intriguing, but a bit far-fetched. I liked the characters he created and would like to now read his other books.
Aug 29, 2014 rated it liked it  ·  review of another edition
This story was headed for a higher rating until its ending. While interesting throughout, too many good characters pay with their limbs or their lives and thereby diminish this novel. Good people are not chattel. 6 of 10 stars
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Michael Palmer, M.D., 1942-2013, was the author of Political Suicide, Oath of Office, A Heartbeat Away, The Last Surgeon, The Second Opinion, The First Patient, The Fifth Vial, The Society, Fatal, The Patient, Miracle Cure, Critical Judgment, Silent Treatment, Natural Causes, Extreme Measures, Flashback, Side Effects, and The Sisterhood. His books have been translated into thirty-five languages.


Other books in the series

Dr. Lou Welcome (3 books)
  • Oath of Office (Dr. Lou Welcome, #1)
  • Political Suicide (Dr. Lou Welcome, #2)
“Prior to their discovery in 1917, phages had been linked to miracle waters—rivers in India and other places with the power to cure diseases from leprosy to cholera. Only later did scientists, examining a naturally occurring treatment for dysentery, discover these “cures” were phages, feasting on and eradicating the disease-causing bacteria.” 3 likes
“The only entitlement guaranteed should be the fruits of one’s own labor.” 2 likes
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