I have never been a great follower of art, but reading this selection has awakened an interest. Vasari's prose style is lively and readable, and he even knew some of the great Renaissance artists personally, not to mention being an artist of middling fame in his own right. Translator's footnotes indicate that some of his dates and ages are wrong for artists that he did not know, but this is perhaps forgiveable considering how difficult it is even for modern researchers to pin down often poorly-documented lives. This was the first work of its kind since classical times, after all.
The parts of the book that engaged me most fully pertained to Toscana, and in particular Florence, as I now know it slightly. It is startling to just what an extent the Renaissance in art was a Tuscan affair, and having visited a couple of times I find Vasari speaking of doors and domes that I have seen at close quarters. This renders the writing so much more accessible that I would go so far as to say you should view some of the works or places before reading. The Porta del Paradiso by Ghiberti, for instance, has to be seen to be believed, and reading this book places it in a living context.
It is particularly striking that so many of the artists were so polymathic in their talents. Many were accomplished in painting, sculpture and architecture all at once. I have tended to think of architecture as a primarily engineering discipline, but an acquaintance who is studying architecture in his first year reports that it is a firmly artistic course of study. Reading about Brunelleschi and Michelangelo, one begins to understand how this came to be.
I would hesitate to name a favourite Life. The one weakness I found is that the stories focus almost entirely on the works of the artists rather than their lives. The classic genius of the period is, of course, Leonardo, who had a bad habit of leaving work unfinished, but his polished charm, physical strength, personal elegance and prodigious creative output take the biscuit. The notoriously obnoxious Michelangelo, by contrast, comes across in Vasari's Life as more understandable and principled that I might have expected, not to mention more professional and consistent. Purely based on those doors, I might plump for Lorenzo Ghiberti. Go and see them.
The Renaissance is recorded as the rebirth of classical art and thinking, but interestingly enough it began to ignite spontaneously. Roman sculpture was excavated and studied once the Renaissance was in progress, but the study of perspective and the advances over the flat Byzantine style began earlier. More than I thought, this was a truly Tuscan achievement, and may perhaps be most truly traced back to the growth of political liberalism.