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160 pages, Paperback
First published October 8, 2003
Reading, when reduced to the rather prosaic level of motor actions, depends on the brain’s ability to orchestrate a series of eye movements. Now, as you read these words, your brain is commanding your eyes to make small but very rapid (about 500° per second) left-to-right movements called saccades (right-to-left or up-and-down for some other written languages). You are not consciously aware of it, but these rapid movements are frequently interrupted by brief periods when the eyes are fixed in position. Watch someone reading and you will see exactly what I mean. You’ll notice that the eyes do not sweep smoothly along the line of text, rather they dart from one ��xation to another. It is only during the fixations, when the eyes dwell for about a fifth of a second, that the brain is able to examine the text in detail. Reading is not possible during the darting saccadic movements because the eyes are moving too quickly across the page. You are not aware of the blur and confusion during a saccade because fortunately there is a brain mechanism that suppresses vision and protects you from visual overload.
Highly specialized protein molecules called ion channels restrict this passage of sodium and potassium into and out of the neuron by acting as molecular gatekeepers. Mobile parts of the molecule, ‘gates’, open and close in an orderly sequence. This molecular machinery enables the membrane to control the switching on and off of the sodium and potassium batteries. Each potassium channel has a single gate, known as the activation gate because when opened the flow of potassium is activated. The sodium channel is more complicated and has two gates, the activation gate and an inactivation gate. When the sodium activation gates are open sodium floods into the neuron due to the concentration gradient. This is equivalent to turning ON the 50mv sodium battery, making the inside of the neuron reach its maximum positive potential
of +50mv at the peak of the nerve impulse. When the potassium gates open, equivalent to turning ON the −70mv battery, potassium flows out.